G. Heilek: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Optimal Detection of Fetal Chromosomal Abnormalities by Massively Parallel DNA Sequencing of Cell-Free Fetal DNA from Maternal Blood

Sehnert, A. J., Rhees, B., Comstock, D., de Feo, E., Heilek, G., Burke, J., Rava, R. P.

Journal:

Clinical Chemistry

Year:

2011

Language:

english

File:

PDF, 264 KB

english, 2011

2

Differences in labile soil organic matter explain potential denitrification and denitrifying communities in a long-term fertilization experiment

Surey, Ronny, Lippold, Eva, Heilek, Stefan, Sauheitl, Leopold, Henjes, Sina, Horn, Marcus A., Mueller, Carsten W., Merbach, Ines, Kaiser, Klaus, BÃ¶ttcher, JÃ¼rgen, Mikutta, Robert

Journal:

Applied Soil Ecology

Year:

2020

File:

PDF, 1.12 MB

2020

3

2′-Deoxy-nucleoside Analogs can be Potent Dual Inhibitors of HCV and HIV Replication with Selectivity against Human Polymerases

Klaus Klumpp, Guoping Su, Vincent Leveque, Jerome Deval, Gabrielle Heilek, Sonal Rajyaguru, Yu Li, Julie Q. Hang, Han Ma, Nicole Inocencio, Genadiy Kalayanov, Anna Winqvist, David B. Smith, Nick Camma

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 69 KB

english, 2009

4

Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists

Rémy C. Lemoine, Ann C. Petersen, Lina Setti, Lijing Chen, Jutta Wanner, Andreas Jekle, Gabrielle Heilek, André deRosier, Changhua Ji, David M. Rotstein

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 286 KB

english, 2010

5

Epitope Switching as a Novel Escape Mechanism of HIV to CCR5 Monoclonal Antibodies

Jekle, A., Chhabra, M., Lochner, A., Meier, S., Chow, E., Brandt, M., Sankuratri, S., Cammack, N., Heilek, G.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2010

Language:

english

File:

PDF, 1.99 MB

english, 2010

6

Discovery of a potent, selective and orally bioavailable 3,9-diazaspiro[5.5]undeca-2-one CCR5 antagonist

Hanbiao Yang, Xiao-Fa Lin, Fernando Padilla, Stephen D. Gabriel, Gabrielle Heilek, Changhua Ji, Surya Sankuratri, André deRosier, Pamela Berry, David M. Rotstein

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 215 KB

english, 2009

7

Second-Generation Cobas AmpliPrep/Cobas TaqMan HCV Quantitative Test for Viral Load Monitoring: a Novel Dual-Probe Assay Design

Zitzer, H., Heilek, G., Truchon, K., Susser, S., Vermehren, J., Sizmann, D., Cobb, B., Sarrazin, C.

Journal:

Journal of Clinical Microbiology

Year:

2013

Language:

english

File:

PDF, 951 KB

english, 2013

8

Erratum: Structure and function of ribosomal RNA

Noller, Harry F., Green, Rachel, Heilek, Gabriele, Hoffarth, Vernita, Hüttenhofer, Alexander, Joseph, Simpson, Lee, Inho, Lieberman, Kate, Mankin, Alexander, Merryman, Chuck, Powers, Ted, Puglisi, Eli

Journal:

Biochemistry and Cell Biology

Year:

1996

Language:

english

File:

PDF, 71 KB

english, 1996

9

Synthesis, SAR and evaluation of [1,4′]-bipiperidinyl-4-yl-imidazolidin-2-one derivatives as novel CCR5 antagonists

David M. Rotstein, Stephen D. Gabriel, Nicole Manser, Lubov Filonova, Fernando Padilla, Surya Sankuratri, Changhua Ji, Andre deRosier, Marianna Dioszegi, Gabrielle Heilek, Andreas Jekle, Paul Weller,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 732 KB

english, 2010

10

Probing the rRNA environment of ribosomal protein S5 across the subunit interface and inside the 30 S subunit using tethered Fe(II)

Gloria M Culver, Gabriele M Heilek, Harry F Noller

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 261 KB

english, 1999

11

952 2′ -DEOXY-NUCLEOSIDE ANALOGS AS POTENT DUAL INHIBITORS OF HCV AND HIV REPLICATION, WITH SELECTIVITY AGAINST OTHER VIRAL AND HUMAN POLYMERASES

K. Klumpp, G. Su, J. Deval, V. Leveque, A. Jekle, S. Rajyaguru, P. Gee, Y. Li, J. Hang, H. Ma, N. Inocencio, G. Kalayanov, A. Winqvist, D. Smith, N. Cammack, N.G. Johansson, G. Heilek, I. Najera

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 124 KB

english, 2009

12

Evaluation of the COBAS® AmpliPrep/COBAS® TaqMan® HCV Test, v2.0 and comparison to assays used in routine clinical practice in an international multicenter clinical trial: The ExPECT study

Kessler, Harald H., Cobb, Bryan R., Wedemeyer, Heiner, Maasoumy, Benjamin, Michel-Treil, Veronique, Ceccherini-Nelli, Luca, Bremer, Birgit, Hübner, Margit, Helander, Anna, Khiri, Hacene, Heilek, Gabri

Journal:

Journal of Clinical Virology

Year:

2015

Language:

english

File:

PDF, 450 KB

english, 2015

13

Evaluation of secondary amide replacements in a series of CCR5 antagonists as a means to increase intrinsic membrane permeability. Part 1: Optimization of gem-disubstituted azacycles

Rémy C. Lemoine, Ann C. Petersen, Lina Setti, Jutta Wanner, Andreas Jekle, Gabrielle Heilek, André deRosier, Changhua Ji, Pamela Berry, David Rotstein

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 643 KB

english, 2010

14

Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities

Changhua Ji, Michael Brandt, Marianna Dioszegi, Andreas Jekle, Stephan Schwoerer, Steven Challand, Jun Zhang, Yun Chen, Lisa Zautke, Gunthar Achhammer, Monika Baehner, Sandra Kroetz, Gabrielle Heilek-

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 953 KB

english, 2007

15

2′- and 4′-Modified Ribonucleoside Analogs Can Inhibit All Four Serotypes of Dengue Virus in Human Primary Dendritic Cells as Competitive Inhibitors and Non-obligatory Chain Terminators

Hassan Javanbakht, Vincent Leveque, Zhinan Jin, Jerome Deval, Andreas Jekle, Gabrielle Heilek, Han Ma, Klaus Klumpp

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 69 KB

english, 2011

16

In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor

H. Javanbakht, R.G. Ptak, E. Chow, J.M. Yan, J.D. Russell, M.K. Mankowski, P.A. Hogan, J.H. Hogg, H. Vora, J.Q. Hang, Y. Li, G. Su, A. Paul, N. Cammack, K. Klumpp, G. Heilek

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 219 KB

english, 2010

17

A Novel Substrate-Based HIV-1 Protease Inhibitor Drug Resistance Mechanism

Nijhuis, Monique, van Maarseveen, Noortje M., Lastere, Stephane, Schipper, Pauline, Coakley, Eoin, Glass, Bärbel, Rovenska, Mirka, de Jong, Dorien, Chappey, Colombe, Goedegebuure, Irma W., Heilek-Snyd

Journal:

Year:

2007

Language:

english

File:

PDF, 400 KB

english, 2007

18

Characterization of Envelope Glycoprotein gp41 Genotype and Phenotypic Susceptibility to Enfuvirtide at Baseline and on Treatment in the Phase III Clinical Trials TORO-1 and TORO-2

Melby, T., Sista, P., DeMasi, R., Kirkland, T., Roberts, N., Salgo, M., Heilek-Snyder, G., Cammack, N., Matthews, T.J., Greenberg, M.L.

Journal:

AIDS Research and Human Retroviruses

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

19

Directed hydroxyl radical probing of 16S rRNA using Fe(II) tethered to ribosomal protein S4.

Heilek, G. M., Marusak, R., Meares, C. F., Noller, H. F.

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.07 MB

english, 1995

20

Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase

Zachary K. Sweeney, Sahaja Acharya, Andrew Briggs, James P. Dunn, Todd R. Elworthy, Jennifer Fretland, Anthony M. Giannetti, Gabrielle Heilek, Yu Li, Ann C. Kaiser, Michael Martin, Y. David Saito, Mar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 177 KB

english, 2008

21

Perioperative Antibiotikaprophylaxe

Reutter, F., Reuter, D.A., Hilgarth, H., Heilek, A.M., Goepfert, M.S., Punke, M.A.

Journal:

Der Anaesthesist

Year:

2014

Language:

german

File:

PDF, 713 KB

german, 2014

22

Site-Directed Hydroxyl Radical Probing of the rRNA Neighborhood of Ribosomal Protein S5

Heilek, G. M., Noller, H. F.

Journal:

Year:

1996

Language:

english

File:

PDF, 707 KB

english, 1996

23

Diagnosis and Monitoring of HCV infection using the cobas ® HCV test for use on the cobas ® 6800/8800 system

Yao, Joseph D., Young, Stephen, Heilek, Gabrielle M., Marino, Enrique, Paxinos, Ellen E., Marins, Ed G., Valsamakis, Alexandra

Journal:

Journal of Clinical Virology

Year:

2018

Language:

english

File:

PDF, 1.41 MB

english, 2018

24

CD4-anchoring HIV-1 Fusion Inhibitor with Enhanced Potency and in Vivo Stability

Ji, C., Kopetzki, E., Jekle, A., Stubenrauch, K.-G., Liu, X., Zhang, J., Rao, E., Schlothauer, T., Fischer, S., Cammack, N., Heilek, G., Ries, S., Sankuratri, S.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 1.15 MB

english, 2009

25

Directed Hydroxyl Radical Probing of 16S rRNA Using Fe(II) Tethered to Ribosomal Protein S4

Gabriele M. Heilek, Rosemary Marusak, Claude F. Meares and Harry F. Noller

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 892 KB

english, 1995

26

HIV‐1 Coreceptor Use in Triple‐Class Treatment–Experienced Patients: Baseline Prevalence, Correlates, and Relationship to Enfuvirtide Response

Melby, Tom, DeSpirito, Michael, DeMasi, Ralph, Heilek‐Snyder, Gabrielle, Greenberg, Michael L., Graham, Neil

Journal:

The Journal of Infectious Diseases

Year:

2006

Language:

english

File:

PDF, 381 KB

english, 2006

27

Genotypic changes in human immunodeficiency virus type 1 envelope glycoproteins on treatment with the fusion inhibitor enfuvirtide and their influence on changes in drug susceptibility in vitro

C. Su, T. Melby, R. DeMasi, P. Ravindran, G. Heilek-Snyder

Journal:

Journal of Clinical Virology

Year:

2006

Language:

english

File:

PDF, 210 KB

english, 2006

28

Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc

Rémy C. Lemoine, Ann C. Petersen, Lina Setti, Thomas Baldinger, Jutta Wanner, Andreas Jekle, Gabrielle Heilek, André deRosier, Changhua Ji, David M. Rotstein

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 349 KB

english, 2010

29

CD4-BFFI: A novel, bifunctional HIV-1 entry inhibitor with high and broad antiviral potency

Andreas Jekle, Eugene Chow, Erhard Kopetzki, Changhua Ji, Mei Jun Yan, Rosa Nguyen, Surya Sankuratri, Nick Cammack, Gabrielle Heilek

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 643 KB

english, 2009

30

Exploration of a new series of CCR5 antagonists: Multi-dimensional optimization of a sub-series containing N-substituted pyrazoles

Rémy C. Lemoine, Ann C. Petersen, Lina Setti, Andreas Jekle, Gabrielle Heilek, André deRosier, Changhua Ji, Pamela Berry, David M. Rotstein

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 394 KB

english, 2010

31

Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase

Zachary K. Sweeney, James P. Dunn, Yu Li, Gabrielle Heilek, Pete Dunten, Todd R. Elworthy, Xiaochun Han, Seth F. Harris, Donald R. Hirschfeld, J. Heather Hogg, Walter Huber, Ann C. Kaiser, Denis J. Ke

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 268 KB

english, 2008

32

HCV RNA detection in HCV antibody-positive patients with the COBAS® AmpliPrep/COBAS® TaqMan® HCV test, v2.0 in comparison with FDA-approved nucleic acid tests

Butcher, Ann, Aslam, Shagufta, Hemyari, Pari, Cowen, Ula, Heilek, Gabrielle

Journal:

Journal of Clinical Virology

Year:

2014

Language:

english

File:

PDF, 136 KB

english, 2014

33

Diphenyl Ether Non-Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties

Zachary K. Sweeney, Joshua J. Kennedy-Smith, Jeffrey Wu, Nidhi Arora, J. Roland Billedeau, James P. Davidson, Jennifer Fretland, Julie Q. Hang, Gabrielle M. Heilek, Seth F. Harris, Donald Hirschfeld,

Journal:

Year:

2009

Language:

english

File:

PDF, 521 KB

english, 2009

34

Substrate Envelope and Drug Resistance: Crystal Structure of RO1 in Complex with Wild-Type Human Immunodeficiency Virus Type 1 Protease

Prabu-Jeyabalan, M., King, N. M., Nalivaika, E. A., Heilek-Snyder, G., Cammack, N., Schiffer, C. A.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2006

Language:

english

File:

PDF, 297 KB

english, 2006

35

Association between specific enfuvirtide resistance mutations and CD4 cell response during enfuvirtide-based therapy

Melby, Thomas E, DeSpirito, Michael, DeMasi, Ralph A, Heilek, Gabrielle, Thommes, James A, Greenberg, Michael L, Graham, Neil

Journal:

Year:

2007

Language:

english

File:

PDF, 232 KB

english, 2007

36

Cover Picture: Diphenyl Ether Non-Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties (ChemMedChem 1/2009)

Zachary K. Sweeney, Joshua J. Kennedy-Smith, Jeffrey Wu, Nidhi Arora, J. Roland Billedeau, James P. Davidson, Jennifer Fretland, Julie Q. Hang, Gabrielle M. Heilek, Seth F. Harris, Donald Hirschfeld,

Journal:

Year:

2009

Language:

english

File:

PDF, 879 KB

english, 2009

37

Structure and function of ribosomal RNA

Noller, Harry F., Green, Rachel, Heilek, Gabriele, Hoffarth, Vernita, Hüttenhofer, Alexander, Joseph, Simpson, Lee, Inho, Lieberman, Kate, Mankin, Alexander, Merryman, Chuck, Powers, Ted, Puglisi, Eli

Journal:

Biochemistry and Cell Biology

Year:

1995

Language:

english

File:

PDF, 1.84 MB

english, 1995

38

Molecular diagnostics in the management of chronic hepatitis C: key considerations in the era of new antiviral therapies

Cobb, Bryan, Heilek, Gabrielle, Vilchez, Regis A

Journal:

BMC Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 385 KB

english, 2014

39

Evaluation of amide replacements in CCR5 antagonists as a means to increase intrinsic permeability. Part 2: SAR optimization and pharmacokinetic profile of a homologous azacyle series

Jutta Wanner, Lijing Chen, Rémy C. Lemoine, Rama Kondru, Andreas Jekle, Gabrielle Heilek, André deRosier, Changhua Ji, Pamela W. Berry, David M. Rotstein

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 928 KB

english, 2010

40

Synthesis and biological activity of new pyridone diaryl ether non-nucleoside inhibitors of HIV-1 reverse transcriptase

Arora, Nidhi, Billedeau, J. Roland, Fretland, Jennifer, Hang, Julie Q., Heilek, Gabrielle M., Harris, Seth F., Hirschfeld, Donald, Javanbakht, Hassan, Li, Yu, Kennedy-Smith, Joshua J.

Journal:

Year:

2010

Language:

english

File:

PDF, 176 KB

english, 2010

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски